401-8625-00L Statistical Methods in Clinical Research (University of Zurich)
|Semester||Autumn Semester 2015|
|Periodicity||yearly recurring course|
|Language of instruction||English|
|Comment||No enrolment to this course at ETH Zurich. Book the corresponding module directly at UZH.|
UZH Module Code: STA404
Mind the enrolment deadlines at UZH:
|Abstract||Discussion of the different statistical methods that are used in clinical research.|
|Content||Discussion of the different statistical methods that are used in|
clinical research. Among other subjects the following will be
introduced: sample size calculation, randomization and blinding,
analysis of clinical trials (parallel groups design, analysis of
covariance, crossover design, equivalence studies), intention-to-treat
analysis, multiple testing, group sequential methods, adaptive designs,
diagnostic studies, and agreement studies.
|Literature||- Matthews, J. N. S. (2006). Introduction to Randomized Controlled|
Clinical Trials. Chapman & Hall/CRC Texts in Statistical Science.
- Cook, T. D. and DeMets, L. D. (2008). Introduction to Statistical
Methods for Clinical Trials. Chapman & Hall/CRC Texts in Statistical
- Pepe, M. (2003). The Statistical Evaluation of Medical Tests for
Classification and Prediction. Oxford University Press.
- Schumacher, M. and Schulgen, G. (2008). Methodik klinischer
Studien. Springer, Berlin.
|Prerequisites / Notice||Basic knowlegde of the programming language R, sufficient knowledge in|
calculus, linear algebra, probability, statistics