Autumn Semester 2020 takes place in a mixed form of online and classroom teaching.
Please read the published information on the individual courses carefully.

401-8625-00L  Statistical Methods in Clinical Research (University of Zurich)

SemesterAutumn Semester 2015
LecturersUniversity lecturers
Periodicityyearly recurring course
Language of instructionEnglish
CommentNo enrolment to this course at ETH Zurich. Book the corresponding module directly at UZH.
UZH Module Code: STA404

Mind the enrolment deadlines at UZH:
http://www.uzh.ch/studies/application/mobilitaet_en.html


AbstractDiscussion of the different statistical methods that are used in clinical research.
Objective
ContentDiscussion of the different statistical methods that are used in
clinical research. Among other subjects the following will be
introduced: sample size calculation, randomization and blinding,
analysis of clinical trials (parallel groups design, analysis of
covariance, crossover design, equivalence studies), intention-to-treat
analysis, multiple testing, group sequential methods, adaptive designs,
diagnostic studies, and agreement studies.
Literature- Matthews, J. N. S. (2006). Introduction to Randomized Controlled
Clinical Trials. Chapman & Hall/CRC Texts in Statistical Science.
- Cook, T. D. and DeMets, L. D. (2008). Introduction to Statistical
Methods for Clinical Trials. Chapman & Hall/CRC Texts in Statistical
Science.
- Pepe, M. (2003). The Statistical Evaluation of Medical Tests for
Classification and Prediction. Oxford University Press.
- Schumacher, M. and Schulgen, G. (2008). Methodik klinischer
Studien. Springer, Berlin.
Prerequisites / NoticeBasic knowlegde of the programming language R, sufficient knowledge in
calculus, linear algebra, probability, statistics