Autumn Semester 2020 takes place in a mixed form of online and classroom teaching.
Please read the published information on the individual courses carefully.

Search result: Catalogue data in Spring Semester 2016

Health Sciences and Technology Bachelor Information
First Year Compulsory Subjects
First Year Examinations
NumberTitleTypeECTSHoursLecturers
551-0106-00LFundamentals of Biology IBO5 credits5GS. C. Zeeman, W. Krek, J. Levine, O. Y. Martin, G. Velicer, A. Wutz
AbstractThis course is an introduction into the basic principles of evolution, diversity, animal/plant form and function, and ecology.
ObjectiveIntroduction into aspects of modern biology and fundamental biological concepts.
ContentThe course is divided into distinct chapters
1. Mechanisms of evolution.
2. The evolutionary history of biological diversity (bacteria and archea, protists, plants and animals).
3. Plant form and function (growth and development, nutrient and resource acquisition, reproduction and environmental responses).
4. Animal form and function (nutrition, immune system, hormones, reproduction, nervous system and behaviour).
5. Ecology (population ecology, community ecology, ecosystems and conservation ecology).
Lecture notesNo script
LiteratureThis course is based on the textbook 'Biology' (Campbell, Reece, 9th edition). The structure of the course follows that of the book. It is recommended to purchase the English version.
Prerequisites / NoticePart of the contents of the book need to be learned through independent study.
529-1012-00LOrganic Chemistry II (for Students of Biology, Pharmaceutical Sci., and Health Sci. & Tech.)O5 credits5GC. Thilgen
AbstractThe key relation between structure and reactivity of organic molecules is recognized by studying the mechanisms of the fundamental types of organic reactions. A basic synthesis repertoire is concomitantly acquired.
ObjectiveUnderstanding the mechanisms of the fundamental types of organic reactions. Particular emphasis is placed on the relationship between structure and reactivity. A basic repertoire for the synthesis of small organic molecules is gradually acquired. Weekly problem solving lessons facilitate a deeper understanding of the concepts presented during the lecture.
ContentPresentation of the fundamental reactions of organic chemistry and their mechanisms. Chemistry of the most important functional groups, the carbonyl group in particular.

For details, see German version.
Lecture notesPrinted lecture notes are available for purchase at the beginning of the semester. Problem sets, answer keys, and other course materials can be downloaded from the Moodle course "Organic Chemistry II" of the current semester (https://moodle-app2.let.ethz.ch).
LiteratureNo set textbooks. Optional texts will be proposed at the beginning of the class and in the lecture notes (cf. course 529-1011-00L Organic Chemistry I).
Prerequisites / NoticeAttendance of the course 529-1011-00, "Organic Chemistry I for Biology/Pharmaceutical Sciences/HST".
376-0001-00LBiomechanics I Restricted registration - show details O5 credits3V + 2UJ. G. Snedeker
AbstractIntroduction to engineering mechanics with applications in biology and medicine: kinematics and statics of rigid bodies and systems. Basic introduction to deformation and failure of materials under load.
ObjectiveStudents can solve problems of elementary engineering mechanics, and understand how these are relevant to biology and medicine.
ContentBasic notions: position and velocitiy of particles, rigid bodies, planar motion, kinematics of rigid body, force, couple, power.
Statics: static equivalence, force-couple system, center of forces, centroid, principle of virtual power, equilibrium, constraints, statics, friction.
Effects of mechanical load, and material stresses and deformation in tension, compression, bending, and torsion.
Lecture notesYes
LiteratureM. B. Sayir, J. Dual, S. Kaufmann: Ingenieurmechanik 1, Grundlagen und Statik. Vieweg + Teubner, Wiesbaden, 2008.
M. B. Sayir, S. Kaufmann: Ingenieurmechanik 3, Dynamik. Teubner, Stuttgart, 2005.
401-0292-00LMathematics IIO5 credits3V + 2UA. Caspar
AbstractMathematics I/II is an introduction to one- and multidimensional calculus
and linear algebra emphasizing on applications.
ObjectiveStudents understand mathematics as a language for modelling and as a tool for
solving practical problems in natural sciences.
Students can analyze models, describe solutions qualitatively or calculate
them explicitly if need be. They can solve examples as well as their practical
applications manually and using computer algebra systems.
Content## Lineare Algebra ##
- Weitere Arithmetische Aspekte
- LGS und Gauss-Verfahren

## Komplexe Zahlen ##
- Kartesische und Polar-Darstellung
- Rechnen mit komplexen Zahlen
- Lösungen algebraischer Gleichungen
- Komplexe Vektoren und Matrizen

## Lineare DGL 2. Ordnung und Systeme 1. Ordnung ##
- Lösen mit Eigenwerten/-vektoren.
- Qualitative Lösungsverhalten

## Integralrechnung (II) ##
- Hauptsatz der Differential/Integralrechnung
- Uneigentliche Integrale
- Anwendungen
- Gebiets- und Volumenintegral

## Differentialrechnung (II) ##
- Partielle Funktionen und Ableitungen
- Extrema
- Tangentialebene
- Verallgemeinerte Kettenregel

## Vektoranalysis ##
- Ebene und Räumliche Kurven
- Potentialtheorie
- Formel von Green
- Rotation und Divergenz
- Oberflächenintegral, Fluss
- Integralsätze von Gauss und Stokes.

## Potenzreihen ##
- Reihen
- Taylor-Polynom/Reihe
- Potenzreihen und Anwendungen
Lecture notesIn Ergänzung zu den Vorlesungskapiteln der Lehrveranstaltungen fassen wir
wichtige Sachverhalte, Formeln und weitere Ausführungen jeweils in einem
Vademecum zusammen. Die pdfs finden Sie unter Lernmaterial > Dokumente.

Dabei gilt:

* Die Skripte ersetzen nicht die Vorlesung und/oder die Übungen!
* Ohne den Besuch der Lehrveranstaltungen verlieren die Ausführungen
ihren Mehrwert.
* Details entwickeln wir in den Vorlesungen und den Übungen, um die hier
bestehenden Lücken zu schliessen.
* Prüfungsrelevant ist, was wir in der Vorlesung und in den Übungen behandeln.
Literature**Th. Wihler**
Mathematik für Naturwissenschaften, 2 Bände:
Einführung in die Analysis, Einführung in die Lineare Algebra;
Haupt-Verlag Bern, UTB.

**H. H. Storrer**
Einführung in die mathematische Behandlung der Naturwissenschaften I; Birkhäuser.
Via ETHZ-Bibliothek:
<http://link.springer.com/book/10.1007/978-3-0348-8598-0/page/1>

**Ch. Blatter**
Lineare Algebra; VDF
auch als [pdf]<https://people.math.ethz.ch/~blatter/linalg.pdf>
Prerequisites / Notice## Voraussetzungen ##

Mathematik I <Link>

## Übungen und Prüfungen ##
+ Die Übungsaufgaben (inkl. Multiple-Choice) sind ein wichtiger Bestandteil
der Lehrveranstaltung.
+ Es wird erwartet, dass Sie mindestens 75 % der wöchentlichen Serien bearbeiten
und zur Korrektur einreichen.
+ Der Prüfungsstoff ist eine Auswahl von Themen aus Vorlesung und Übungen. Für
eine erfolgreiche Prüfung ist die konzentrierte Bearbeitung der Aufgaben
unerlässlich.

## Einschreibung in die Übungen ##
Die Einschreibung in die Übungsgruppen erfolgt online.
Alle unter http://www.mystudies.ethz.ch/ für die Vorlesung Eingeschriebenen
erhalten rechtzeitig per Email einen personalisierten Link zur Einschreibung.
Behalten Sie diesen Link.

## Zugang Übungsserien ##
Erfolgt auch online.
Alle unter http://www.mystudies.ethz.ch/ für die Vorlesung Eingeschriebenen
erhalten rechtzeitig per Email einen 2. personalisierten Link.
Behalten Sie auch diesen Link.
401-0643-00LStatistics I Information O3 credits2V + 1UM. Kalisch
AbstractIntroduction to basic methods and fundamental concepts of statistics and probability theory for non-mathematicians. The concepts are presented on the basis of some descriptive examples.
ObjectiveGrundverständnis für die Gesetze des Zufalls und des Denkens in Wahrscheinlichkeiten. Kenntnis von Methoden zur Darstellung von Daten und zu ihrer quantitativen Interpretation unter Berücksichtigung der statistischen Unsicherheit.
ContentModelle und Statistik für Zähldaten: Diskrete Wahrscheinlichkeitsmodelle, Binomial-Verteilung, Tests und Vertrauensintervalle für eine Wahrscheinlichkeit, Poisson-Verteilung und deren Statistik, weitere Verteilungen.
Modelle und Statistik für Messdaten: Beschreibende Statistik, Zufallsvariablen mit Dichten, t-Test und Wilcoxon-Test und zugehörige Vertrauensintervalle.
Regression: Das Modell der linearen Regression, Tests und Vertrauensintervalle, Residuenanalyse.
Lecture notesEs steht ein kurzes Skript zur Verfügung.
Literature- W. A. Stahel, Statistische Datenanalyse: Eine Einführung für Naturwissenschaftler, 4. Aufl., Vieweg, Braunschweig/Wiesbaden, 2002
Prerequisites / NoticeVoraussetzungen: Grundlegende Mathematik-Kenntnisse wie sie im ersten Semester erworben werden.

Diese Lerneinheit:wurde bis zum HS 2013 als 401-0643-00L Statistik angeboten.
376-0004-00LIntroduction to Health Sciences and Technology II Restricted registration - show details O2 credits2VR. Müller
AbstractIntroduction to the five majors of the curriculum based on typical research questions: Human Movement Science and Sport, Health Technologies, Neurosciences, Molecular Health Sciences, and Human Health, Nutrition and Environment. Outline of different job opportunities in biomedical science, medical engineering, health promotion and other areas.
ObjectiveStudents will learn about real research processes and job opportunities in the area of Health Sciences and Technology.
First Year Laboratory Courses
NumberTitleTypeECTSHoursLecturers
376-0010-00LLaboratory Course in Chemistry Restricted registration - show details O2 credits2PW. Uhlig, N. Kobert
AbstractBasic techniques of experimentak chemistry are learned.
The experiments include analytical and preparative duties. Selected synthesis are carried out and chemical substances are analysed. The handling of gaseous substances in the laboratory is practiced.
ObjectiveInsight into experimental methods of chemistry: Behaviour in the laboratory, handling of chemical substances, observation and description of basic chemical reactions.
Content- Analytik - Nitratbestimmung
- Komplexe - Löslichkeit
- Chemische Synthesen (Bsp. Aspirin)
- Protonenübertragung in wässriger Lösung
- Lebensmittelfarbstoffe
- Gaschromatographie
Lecture notesDas Skript zum Praktikum und die Versuchsanleitungen werden auf einer eigenen homepage zugänglich gemacht.
LiteratureDie genaue Vorbereitung anhand des Praktikumsskripts ist Voraussetzung für die Teilnahme am Praktikum.
376-0004-01LLab Introduction to Health Sciences and Technology Restricted registration - show details
Exclusively for Health Sciences and Technology BSc students.
O2 credits2PR. Müller, W. Langhans, A. Mansouri, R. Riener, C. Wolfrum
AbstractSelected experiments in the area of health sciences and technology as introduction to scientific working.
ObjectiveStudents should understand the methods of scientific working which they will apply in various experiments.
Second Year Compulsary Subjects
Examination Blocks
Examination Block 3
NumberTitleTypeECTSHoursLecturers
376-0150-00LAnatomy II, Physiology II and HistologyO6 credits4V + 2GM. Ristow, D. P. Wolfer, G. Colacicco, K. De Bock, A. Oxenius, L. Slomianka, C. Spengler
AbstractBasic knowledge of the anatomy and physiology of the gastrointestinal tract, endocrine organs, urinary system and the reproductive system. Knowlewdge of the basic mechanisms of pathobiology. Study of all human tissues and selected organs by examining slides under the light microscope.
ObjectiveFoundations of human anatomy and physiology and basics of clinical pathophysiology
ContentShort overview of human anatomy, physiology and general pathology.
3rd semester:
Principles of histology and embryology. Anatomy and physiology: nervous system, muscle, sensory organs, circulatory system, respiratory system.
4rd semester:
Anatomy and physiology: gastrointestinal tract, endocrine system, metabolism and thermoregulation, integumentary system, blood and immune system, urinary system, circadian rhythm, reproductive system, pregnancy and birth.
LiteratureAnatomie: Martini, Timmons, Tallitsch, "Anatomie", Pearson; oder Schiebler, Korf, "Anatomie", Steinkopff / Springer;

Physiologie: Thews/Mutschler/Vaupel: Anatomie, Physiologie, Pathophysiologie des Menschen,
Wissenschaftliche Verlagsgesellschaft, Stuttgart

oder

Schmidt/Lang/Thews: Physiologie des Menschen, Springer-Verlag, Heidelberg
Prerequisites / NoticeDer Besuch der Anatomie und Physiologie I - Vorlesung ist Voraussetzung, da die Anatomie und Physiologie II - Vorlesung auf dem Wissen der im vorangegangenen Semester gelesenen Anatomie und Physiologie I - Vorlesung aufbaut.
402-0044-00LPhysics IIO4 credits3V + 1UM. R. Meyer
AbstractIntroduction to the concepts and tools in physics with the help of demonstration experiments: electromagnetism, optics, introduction to modern physics.
ObjectiveThe concepts and tools in physics, as well as the methods of an experimental science are taught. The student should learn to identify, communicate and solve physical problems in his/her own field of science.
ContentElectromagnetism (electric current, magnetic fields, electromagnetic induction, magnetic materials, Maxwell's equations), Optics (light, geometrical optics, interference and diffraction), and Introduction to quantum physics
Lecture notesThe lecture follows the book "Physics for Scientists and Engineers" by Paul A. Tipler and Gene Mosca (6th edition).
LiteraturePhysics for Scientists and Engineers" by Paul A. Tipler and Gene Mosca (6th edition). There is also a similar book in German published by Spektrum Akademischer Verlag authored under the permission of Tipler and Mosca.
Prerequisites / NoticeFor the exam, a self-written summary sheet, hand-held calculator, and translation dictionary (to English).
Examination Block 4
NumberTitleTypeECTSHoursLecturers
376-0008-00LAdvanced Anatomy and Physiology II Information Restricted registration - show details
Only for Health Sciences and Technology BSc.
O4 credits4VK. De Bock, M. Detmar, M. Flück, W. Langhans, C. Spengler, C. Wolfrum, further lecturers
AbstractIn-depth theory to molecular and pathophysiological aspects of nerves, muscles, heart , circulatory , respiratory and sensory organs .
ObjectiveIn-depth knowledge of anatomy and physiology.
ContentMolecular fundamentals of physiological processes, processes of disease development.
376-0206-00LBiomechanics IIO4 credits3GS.  Lorenzetti, R. List, B. Taylor
AbstractIntroduction in dynamics, kinetics and kinematic of rigid and elastic multi-body systems with examples in biology, medicine and especially the human movement
ObjectiveThe students are able
- to analyse and describe dynamic systems
- to explain the mechanical laws and use them in biology and medicine
ContentThe human movement from a mechanical point of view. Kinetic and kinematic concepts and their mechanical description. Energy and momentum of a movement. Mechanical description of a multi-body system.
376-1611-00LBiomedical Interfaces Information O4 credits2V + 1UI. Schön, V. Vogel, R. Konradi
AbstractBased on the understanding of how biomolecules and living cells interact with materials, prototypical requirements for materials and material surfaces are developed.
The concepts are illustrated in the context of specific biomedical applications. I.e. we present strategies that exploit the self-assembly of (bio)molecular building blocks.
ObjectiveUsing the knowledge of cell-to-cell and cell-to-matrix interactions, the students will be able to define essential requirements how to functionalize materials in the context of specific biomedical applications.

Based on the understanding of the basic principles of self-organizing systems, the students will be able to predict shape, size and functional characteristics of a desired structure by choosing adequate molecules and appropriate solution conditions for their assembly. Furthermore, the students will acquire knowledge about methods for the functionalization of conventional materials in order to tailor their biocompatibility or function.

In the accompanying seminar, the students will learn how to address scientific questions by original publications. The students will learn how to read, evaluate, and criticize scientific literature in the context of biomaterials.
Content- protein-surface interactions
- anti-adhesive surface coatings
- biosensors
- bacteria-surface interactions
- cell-nanoparticle interactions
- drug delivery systems
- cell-matrix interactions
- soft tissue engineering
Lecture notesHandouts of the lecture can be accessed online.
LiteratureSelected chapters of
- Biomaterials Science: an Introduction to Materials in Medicine, by B. Ratner, 3rd Ed. Academic Press (2013).
- Biomimetic Materials and Design: Biointerfacial Strategies, Tissue Engineering and Targeted Drug Delivery, by A.K. Dillow and A.M. Lowman, CRC Press (2002).
- Biomaterials: Principles and Practices, by J.Y. Wong et al., CRC Press (2013).
- Molecular Biology of the Cell, by B. Alberts et al., Taylor & Francis, 5th Ed. (2007).
Detailed literature references will be provided in the lectures.
Prerequisites / NoticeThis interdisciplinary class addresses students from all disciplines at the Bachelor level. We premise a profound basic knowledge about cell biology and biochemistry.
Second Year Laboratory Courses
NumberTitleTypeECTSHoursLecturers
376-0006-01LLaboratory Course in Physiology Restricted registration - show details O1 credit1.5PC. Spengler
AbstractExperiments to evaluate nerve, muscle, heart, circulation, respiration, and sensory organ function in humans.
ObjectivePractical experience of physiology. Learning of fundamental assessments of physiological functions in humans and of correct interpretations of measurement data.
ContentDetermination of nerve conduction time, recording of electromyogram (EMG; single stimuli and summatin) and mechanogram; measurement of lung function and oxygen consumption; assessment of cardiovascular adjustments in response to orthostatic challenges and exercise; computer simulation of the cardiovascular system under different conditions; determination of hearing threshold level, visual acuity, accommodation and field of vision.
Lecture notesScriptum of the Laboratory Experiments in Physiology on Moodle
376-0006-02LLaboratory Course in Molecular Biology Restricted registration - show details O2 credits2PC. Wolfrum
AbstractIntroduction to experimental molecular biology using physiological examples.
ObjectivePractical experience of molecular biology. Learning of fundamental research methods.
ContentProtein analysis , cell culture, quantification of RNA.
Lecture notesEin Skript zum Praktikum wird abgegeben.
Third Year Focus Courses
Focus Courses: Human Movement Science and Sport
NumberTitleTypeECTSHoursLecturers
376-0204-00LExercise Sciences Information W4 credits3GE. de Bruin, P. Eggenberger, A. Krebs
AbstractInformation on the structure and function of body systems and how they adapt to several types of training. Motor learning as the learning of skilled behaviors and how it is influenced by practice and feedback. Testing, evaluation, exercise techniques to achieve specific training goals, program design and organization. The theoretical lectures are complemented with practical lab work.
ObjectiveUnderstand how to develop and administer safe and effective strength and conditioning programs.
ContentAdaptations to Anaerobic & Aerobic Training Programs, Resistance Training, Plyometric Training, Speed, Agility, and Speed-Endurance Development, Aerobic Endurance Exercise Training, Periodization, Performance Assessment.Motor Learning Concepts and Research Methods, Conditions of Practice, Augmented Feedback, The Learning Process/Retention & Transfer.
Lecture notesLecture slides and papers on Moodle platform.
Literaturerecommended books:
- Thomas R. Baechle & Roger W. Earle (eds). Essentials of Strength Training and Conditioning (3rd edition). Human Kinetics.

- Jürgen Weineck: Optimales Training

Advanced Fitness Assessment and Exercise Prescription (Vivian H. Heyward, Ann L. Gibson)
376-0202-00LNeural Control of Movement and Motor LearningW4 credits3GN. Wenderoth
AbstractThis course extends the students' knowledge regarding the neural control of movement and motor learning. Particular emphasis will be put on those methods and experimental findings that have shaped current knowledge of this area.
ObjectiveKnowledge of the physiological and anatomic basis underlying the neural control of movement and motor learning. One central element is that students have first hands-on experience in the lab where small experiments are independently executed, analysed and interpreted.
Focus Courses: Molecular Health Sciences
NumberTitleTypeECTSHoursLecturers
551-0326-00LCell Biology Information W6 credits4VS. Werner, U. Auf dem Keller, W. Kovacs, W. Krek, A. M. Kyburz Kooznetsoff, M. Schäfer, U. Suter
AbstractThis Course introduces principle concepts, techniques, and experimental strategies used in modern Cell Biology. Major topics include: neuron-glia interactions in health and disease; mitochondrial dynamics; RNA processing; growth factor action in development, tissue repair and disease; cell metabolism, in particular sensing and signaling mechanisms, cell organelles, and lipid metabolism.
Objective-To prepare the students for successful and efficient lab work by learning how to ask the right questions and to use the appropriate techniques in a research project.
-To convey knowledge about neuron-glia interactions in health and disease.
-To provide information on growth factor signaling in development, repair and disease and on the use of growth factors or their receptors as drug targets for major human diseases
-To convey knowledge on the mechanisms underlying repair of injured tissues
-To provide the students with an overview of mitochondrial dynamics.
-Providing an understanding of RNA processing reactions and their regulations.
-To provide a comprehensive understanding of metabolic sensing mechanisms occurring in different cell types and organelles in response to glucose, hormones, oxygen, nutrients as well as lipids, and to discuss downstream signaling pathways and cellular responses.
-To provide models explaining how disturbances in complex metabolic control networks and bioenergetics can lead to disease and to highlight latest experimental approaches to uncover the intricacies of metabolic control at the cellular and organismal level.
-Providing the background and context that foster cross-disciplinary scientific thinking.
551-1400-00LMolecular Disease Mechanisms IIW6 credits4VC. Wolfrum, M. Kopf, S. J. Sturla, further lecturers
AbstractIn this course the mechanisms of disease development will be studied. Main topics will be:

1. Influence of environmental factors with an emphasis on inflammation and the immune response.
2. Mechanisms underlying disease progression in metabolic disorders, integrating genetic and environmental factors.
3. Mechanisms underlying disease progression in cancer, integrating genetic and environment
ObjectiveTo understand the mechanisms governing disease development with a special emphasis on genetic and environmental associated components
Lecture notesAll information can be found at:

https://moodle-app2.let.ethz.ch/course/view.php?id=690

The enrollment key will be provided by email
Focus Courses: Medical Technology
NumberTitleTypeECTSHoursLecturers
376-0206-00LBiomechanics IIW4 credits3GS.  Lorenzetti, R. List, B. Taylor
AbstractIntroduction in dynamics, kinetics and kinematic of rigid and elastic multi-body systems with examples in biology, medicine and especially the human movement
ObjectiveThe students are able
- to analyse and describe dynamic systems
- to explain the mechanical laws and use them in biology and medicine
ContentThe human movement from a mechanical point of view. Kinetic and kinematic concepts and their mechanical description. Energy and momentum of a movement. Mechanical description of a multi-body system.
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